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PhD

 

Biological research is multidisciplinary and it is crucial to train new generations of researchers to make them able to face the future challenges in life sciences.
The students of the PhD program in Biology have the opportunity to conduct an original research project under the supervision of an academic member of Department of Biology, monitored by the PhD thesis Advisory Committee.
The availability of advanced equipment and technologies, different and interdisciplinary research programs, a wide spectrum of scientific expertise, enables the PhD studentes to acquire a critical spirit in research, as well as methods of investigation and technology applicable in the various fields of modern biological research. In addition to the research activity, the degree program of the PhD students in Biology is enriched with a large program of courses, seminars, workshops and conferences organized by the Department of Biology and the Polytechnic and Basic Sciences School. In this way, PhD students are introduced to many aspects of basic and applied research and carry out a PhD training course adequate for future job opportunities in academic, industrial or public institutions.

Members of the PhD Board (Department of Biology)

  • Avallone Bice
  • Cigliano Luisa
  • Contursi Patrizia
  • Cubellis Maria Vittoria
  • De Falco Maria
  • De Vico Gionata
  • Di Cosmo Anna
  • Esposito Sergio
  • Giordano Simonetta
  • Iossa Susanna
  • Maisto Giulia
  • Majello Barbara
  • Missero Caterina
  • Pollice Alessandra
  • Porcellini Antonio
  • Ricca Ezio
  • Chiurazzi Maurizio – CNR
  • Fontana Angelo – CNR
  • Sanges Remo – Stazione Zoologica Anton Dohrn

 

Dottorato in Biologia XXX cicle

Novembre 1st 2014 –  October 31 st 2017

Dottorato in Biologia XXXI cicle

November 1st 2015 – October 31st 2018

Dottorato in Biologia XXXII cicle

February 1st 2017-  Jenuary 31st 2020

work in progress

30° Ciclo

Andrea Bosso, PhD Student

  • Binding of a type 1 RIP and of its chimeric variant to phospholipid bilayers: evidence for a link between cytotoxicity and protein/membrane interactions.
    Pizzo E., Oliva R., Morra R., Bosso A., Ragucci S., Petraccone L., Del Vecchio P., Di Maro A.
    Biochim Biophys Acta. 2017 Oct;1859(10):2106-2112. doi: 10.1016/j.bbamem.2017.08.004. Epub 2017 Aug 7.
  • A new cryptic host defense peptide identified in human 11-hydroxysteroid dehydrogenase-1 ?-like: from in silico identification to experimental evidence.
    Bosso A., Pirone L., Gaglione R., Pane K., Del Gatto A., Zaccaro L., Di Gaetano S., Diana D., Fattorusso R., Pedone E., Cafaro V., Haagsman H.P., van Dijk A., Scheenstra M.R., Zanfardino A., Crescenzi O., Arciello A., Varcamonti M., Veldhuizen E.J.A., Di Donato A., Notomista E., Pizzo E.
    Biochim Biophys Acta. 2017 Sep;1861(9):2342-2353. doi: 10.1016/j.bbagen.2017.04.009. Epub 2017 Apr 26.
  • Novel human bioactive peptides identified in Apolipoprotein B: Evaluation of their therapeutic potential.
    Gaglione R., Dell’Olmo E., Bosso A., Chino M., Pane K., Ascione F., Itri F., Caserta S., Amoresano A., Lombardi A., Haagsman H.P., Piccoli R., Pizzo E., Veldhuizen E.J.A., Notomista E., Arciello A.
    Biochem Pharmacol. 2017 Apr 15;130:34-50. doi: 10.1016/j.bcp.2017.01.009. Epub 2017 Jan 25.
  • A new active antimicrobial peptide from PD-L4, a type 1 ribosome inactivating protein of Phytolacca dioica L.: A new function of RIPs for plant defence?
    Pizzo E., Zanfardino A., Di Giuseppe AM., Bosso A., Landi N., Ragucci S., Varcamonti M., Notoomista E., Di Maro A.
    FEBS Lett. 2015 Sep 14;589(19 Pt B):2812-8. doi: 10.1016/j.febslet.2015.08.018. Epub 2015 Aug 20.

Heleena Moni Bottu, PhD Student

  • Polyunsaturated Fatty Acids Attenuate Diet Induced Obesity and Insulin Resistance, Modulating Mitochondrial Respiratory uncoupling in Rat Skeletal Muscle.
    Cavaliere G., Trinchese G., Bergamo P., De Filippo C., Mattace Raso G., Gifuni G., Putti R., Moni B.H., Canani R.B., Meli R., Mollica M.P.
    PLoS One. 2016 Feb 22;11(2):e0149033. doi: 10.1371/journal.pone.0149033. eCollection 2016.

 Rosa Cancelliere, PhD Student

  • Fat Quality Influences the Obesogenic Effect of High Fat Diets.
    Crescenzo R., Bianco F., Mazzoli A., Giacco A., Cancelliere R., di Fabio G., Zarrelli A., Liverini G., Iossa S.
    Nutrients. 2015 Nov 16;7(11):9475-91. doi: 10.3390/nu7115480
  • Polyunsaturated Fatty Acids Stimulate De novo Lipogenesis and Improve Glucose Homeostasis during Refeeding with High Fat Diet.
    Crescenzo R., Mazzoli A., Cancelliere R., Bianco F., Giacco A., Liverini G., Dulloo A.G., Iossa S.
    Front Physiol. 2017 Mar 23;8:178. doi: 10.3389/fphys.2017.00178. eCollection 2017
  • Short-Term Fructose Feeding Induces Inflammation and Oxidative Stress in the Hippocampus of Young and Adult Rats.
    Cigliano L., Spagnuolo M.S., Crescenzo R., Cancelliere R., Iannotta L., Mazzoli A., Liverini G., Iossa S.
    Mol Neurobiol. 2017 Apr 28. doi: 10.1007/s12035-017-0518-2. [Epub ahead of print]
  • Dietary fructose causes defective insulin signalling and ceramide accumulation in the liver that can be reversed by gut microbiota modulation.
    Crescenzo R., Mazzoli A., Di Luccia B., Bianco F., Cancelliere R., Cigliano L., Liverini G., Baccigalupi L., Iossa S.
    Food Nutr Res. 2017 Jun 9;61(1):1331657. doi: 10.1080/16546628.2017.1331657. eCollection 2017.
  • Beneficial effects of carotenoid-producing cells of Bacillus indicus HU16 in a rat model of diet-induced metabolic syndrome
    Crescenzo R., Mazzoli A., Cancelliere R., Bucci A., Naclerio G., Baccigalupi L., Cutting S.M., Ricca E., Iossa S.
    Benef Microbes. 2017 Oct 3:1-10. doi: 10.3920/BM2017.0025. [Epub ahead of print].

Mariana Di Lorenzo, PhD Student

  • HSP90 and pCREB alterations are linked to mancozeb-dependent behavioral and neurodegenerative effects in a marine teleost.
    Zizza M., Di Lorenzo M., Laforgia V., Furia E., Sindona G., Canonaco M., Facciolo R.M.
    Toxicol Appl Pharmacol. 2017 May 15;323:26-35. doi: 10.1016/j.taap.2017.03.018. Epub 2017 Mar 19.
  • Nonylphenol effects on human prostate non tumorigenic cells.
    Forte M., Di Lorenzo M., Carrizzo A., Valiante S., Vecchione C., Laforgia V., De Falco M.
    Toxicology. 2016 May 16;357-358:21-32. doi: 10.1016/j.tox.2016.05.024. Epub 2016 Jun 1.

Francesca Figlioli, PhD Student

  • Tracking the route of phenanthrene uptake in mosses: An experimental trial.
    Spagnuolo V., Figlioli F., De Nicola F., Capozzi F., Giordano S.
    Sci Total Environ. 2017 Jan 1;575:1066-1073. doi: 10.1016/j.scitotenv.2016.09.174. Epub 2016 Sep 29.
  • Ultrastructural, protein and photosynthetic alterations induced by Pb and Cd in Cynara cardunculus L., and its potential for phytoremediation.
    Arena C., Figlioli F., Sorrentino M.C., Izzo L.G., Capozzi F., Giordano S., Spagnuolo V.
    Ecotoxicol Environ Saf. 2017 Nov;145:83-89. doi: 10.1016/j.ecoenv.2017.07.015. Epub 2017 Jul 12.

Vincenzo Migliaccio, PhD Student

  • Diet impact on mitochondrial bioenergetics and dynamics.
    Putti R., Sica R., Migliaccio V., Lionetti L.
    Front Physiol. 2015 Apr 8;6:109. doi: 10.3389/fphys.2015.00109. eCollection 2015. Review.
  • Skeletal Muscle Mitochondrial Bioenergetics and Morphology in High Fat Diet Induced Obesity and Insulin Resistance: Focus on Dietary Fat Source.
    Putti R., Migliaccio V., Sica R., Lionetti L.
    Front Physiol. 2016 Jan 20;6:426. doi: 10.3389/fphys.2015.00426. eCollection 2015. Review.

 31° Ciclo

Vincenza Aliperti, PhD Student

  • Long Non-coding RNA in Neurons: New Players in Early Response to BDNF Stimulation.
    Aliperti V.
    and Donizetti A.Front Mol Neurosci. 2016 Mar 2; 9:15. doi: 10.3389/fnmol.2016.00015. eCollection 2016.
  • Brain-derived neurotrophic factor modulates cholesterol homeostasis and Apolipoprotein E synthesis in human cell models of astrocytes and neurons.Spagnuolo M.S., Donizetti A., Iannotta L., Aliperti V., Cupidi C., Bruni A.C., Cigliano L.Cell Physiol. 2018 Jan 11. doi: 10.1002/jcp.26480.

Chiara Cimmaruta, PhD Student

  • Identification of an Allosteric Binding Site on Human Lysosomal Alpha-Galactosidase Opens the Way to New Pharmacological Chaperones for Fabry Disease.
    Citro V., Peña-García J., den-Haan H., Pérez-Sánchez H., Del Prete R., Liguori L., Cimmaruta C., Lukas J., Cubellis M.V., Andreotti G.
    PLoS One. 2016 Oct 27;11(10):e0165463. doi: 10.1371/journal.pone.0165463. eCollection 2016.
  • The large phenotypic spectrum of Fabry disease requires graduated diagnosis and personalized therapy: a meta-analysis can help to differentiate missense mutations.
    Citro V., Cammisa M., Liguori L., Cimmaruta C., Lukas J., Cubellis M.V., Andreotti G.
    Int J Mol Sci. 2016 Dec 1;17(12). pii: E2010. Review.
  • E-Learning for Rare Diseases: An Example Using Fabry Disease.
    Cimmaruta C
    ., Liguori L., Monticelli M., Andreotti G., Citro V.Int J Mol Sci. 2017 Sep 24;18(10). pii: E2049. doi: 10.3390/ijms18102049.
  • A mutant of phosphomannomutase1 retains full enzymatic activity, but is not activated by IMP: Possible implications for the disease PMM2-CDG.Citro V., Cimmaruta C., Liguori .L, Viscido G., Cubellis M.V., Andreotti G.PLoS One. 2017 Dec 19;12(12):e0189629. doi: 10.1371/journal.pone.0189629. eCollection 2017

Lucia Iannotta, PhD Student

  • Short-Term Fructose Feeding Induces Inflammation and Oxidative Stress in the Hippocampus of Young and Adult Rats.
    Cigliano L., Spagnuolo M.S., Crescenzo R., Cancelliere R., Iannotta L., Mazzoli A., Liverini G., Iossa S.
    Mol Neurobiol. 2017 Apr 28. doi: 10.1007/s12035-017-0518-2. [Epub ahead of print]
  • Brain-derived neurotrophic factor modulates cholesterol homeostasis and Apolipoprotein E synthesis in human cell models of astrocytes and neurons.
    Spagnuolo M.S., Donizetti A., Iannotta L., Aliperti V., Cupidi C., Bruni A.C., Cigliano L.J Cell Physiol. 2018 Jan 11. doi: 10.1002/jcp.26480.

Valeria Paradisone, PhD Student

  • Roles of some nitrogenous compounds protectors in the resistance to zinc toxicity in Lactuca sativa cv. Phillipus and Brassica oleracea cv. Bronco.
    Paradisone V.
    , Barrameda-Medina Y., Montesinos-Pereira D., Romero L., Esposito S., Ruiz J. M.
    Acta Physiol Plant (2015) 37:137 DOI 10.1007/s11738-015-1893-9

Nadia Ruocco, PhD Student

  • Toxic diatom aldehydes affect defence gene networks in sea urchins.
    Varrella S., Romano G., Costantini S., Ruocco N., Ianora A., Bentley M.G., Costantini M.PLoS One. 2016 Feb 25;11(2):e0149734. doi: 10.1371/journal.pone.0149734. eCollection 2016.
  • First morphological and molecular evidence of the negative impact of diatom-derived hydroxyacids on the sea urchin Paracentrotus lividus.
    Varrella S., Romano G., Ruocco N., Ianora A., Bentley M.G., Costantini M.Toxicol Sci. 2016 Jun;151(2):419-33. doi: 10.1093/toxsci/kfw053. Epub 2016 Mar 16.
  • Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7.
    Ruocco N.,
    Varrella S., Romano G., Ianora .A, Bentley M.G., Somma D., Leonardi A., Mellone S., Zuppa A., Costantini M.Aquat Toxicol. 2016 Jul;176:128-40. doi: 10.1016/j.aquatox.2016.04.012. Epub 2016 Apr 22.
  • High-quality RNA extraction from the sea urchin Paracentrotus lividus embryos.
    Ruocco N., Costantini S., Zupo V., Romano G., Ianora A., Fontana A., Costantini M.PLoS One. 2017 Feb 15;12(2):e0172171. doi: 10.1371/journal.pone.0172171. eCollection 2017.
  • New inter-correlated genes targeted by diatom-derived polyunsaturated aldehydes in the sea urchin Paracentrotus lividus.
    Ruocco N., Maria Fedele A., Costantini S., Romano G., Ianora A., Costantini M.Ecotoxicol Environ Saf. 2017 Aug;142:355-362. doi: 10.1016/j.ecoenv.2017.04.022. Epub 2017 Apr 28.

Monica Tizzano, PhD Student

  • Long term exposure to cadmium: Pathological effects on kidney tubules cells in Sparus aurata juveniles.
    Avallone B., Cerciello R., Cretì P., Pizzoleo C., Scudiero R., Tizzano M., Panzuto R., Simoniello P., Montinari M.R., Motta C.M. Aquat Toxicol. 2017 Dec;193:201-209. doi: 10.1016/j.aquatox.2017.10.025. Epub 2017 Oct 28.

Maria Carmen Valoroso, PhD Student

  • Transcriptome-Wide Identification and Expression Analysis of DIVARICATA- an RADIALIS-Like Genes of the Mediterranean Orchid Orchis italica.
    Valoroso M.C.,
    De Paolo S., Iazzetti G., Aceto S.Genome Biol Evol. 2017 Jun 1;9(6). doi: 10.1093/gbe/evx101
  • Evolutionary loss of melanogenesis in the tunicate Molgula occulta.
    Racioppi C., Valoroso M.C., Coppola U., Lowe E.K., Brown C.T., Swalla B.J., Christiaen L., Stolfi A., Ristoratore F.Evodevo. 2017 Jul 18;8:11. doi: 10.1186/s13227-017-0074-x. eCollection 2017

32° Ciclo

Marco Ferniani, PhD Student

  • Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome.
    Russo C., Osterburg C., Sirico A., Antonini D., Ambrosio R., Würz J.M., Rinnenthal J., Ferniani M., Kehrloesser S., Schäfer B., Güntert P., Sinha S., Dötsch V., Missero C.Proc Natl Acad Sci U S A; 2018 Jan 30;115(5):E906-E915. doi: 10.1073/pnas.1713773115. Epub 2018 Jan 16.

Viviana Maresca, PhD Student

  • Effects of triacontanol on ascorbate-glutathione cycle in Brassica napus L. exposed to cadmium-induced oxidative stress.
    Asadi Karam E., Maresca V., Sorbo S., Keramat B., Basile A.
    Ecotoxicol Environ Saf. 2017 Oct;144:268-274. doi: 10.1016/j.ecoenv.2017.06.035. Epub 2017 Jun 20.
  • Pre-birth sense of smell in the wild boar: the ontogeny of the olfactory mucosa.
    Fulgione D., Trapanese M,. Buglione M., Rippa D., Polese G., Maresca V., Maselli V.
    Zoology (Jena). 2017 Aug;123:11-15. doi: 10.1016/j.zool.2017.05.003. Epub 2017 May 17.
  • Interaction of triacontanol and arsenic on the ascorbate-glutathione cycle and their effects on the ultrastructure in Coriandrum sativum L.
    Asadi karam E., Keramat B., Sorbo S., Maresca V., Asrar Z., Mozafari H.
    Environmental and Experimental Botany; 2017, accepted.

Teresa Micillo, PhD Student

  • Metabolic control of immune tolerance in health and autoimmunity.
    Carbone F., La Rocca C., De Candia P., Procaccini C., Colamatteo A., Micillo T., De Rosa V., Matarese G.
    Semin Immunol. 2016 Oct;28(5):491-504. doi: 10.1016/j.smim.2016.09.006. Epub 2016 Oct 5. Review.
  • Immunometabolic profiling of patients with multiple sclerosis identifies new biomarkers to predict disease activity during treatment with interferon beta-1a.
    Lanzillo R., Carbone F., Quarantelli M., Bruzzese D., Carotenuto A., De Rosa V., Colamatteo A., Micillo T., De Luca Picione C., Saccà F., De Rosa A., Moccia M., Brescia Morra .V, Matarese G.Clin Immunol. 2017 Oct;183:249-253. doi: 10.1016/j.clim.2017.08.011. Epub 2017 Aug 18.

Simona Petrelli, PhD Student

  • Unexpected but welcome. Artificially selected traits may increase fitness in wild boar.
    Fulgione D., Rippa D., Buglione M., Trapanese M., Petrelli S., Maselli V.
    Evol Appl. 2016 May 17;9(6):769-76. doi: 10.1111/eva.12383. eCollection 2016 Jul.

Daniela Saccà, PhD Student

  • LSD1 mediates MYCN control of epithelial-mesenchymal transition through silencing of metastatic suppressor NDRG1 gene.
    Ambrosio S., Amente S., Saccà C.D., Capasso M., Calogero R.A., Lania L., Majello B.
    Oncotarget. 2017 Jan 17;8(3):3854-3869. doi: 10.18632/oncotarget.12924.

Stefano Sol, PhD Student

  • The Nitrate Transporter Family Protein LjNPF8.6 Controls the N-Fixing Nodule Activity.
    Valkov V.T., Rogato A., Alves L.M., Sol S., Noguero M., Léran S., Lacombe B., Chiurazzi M.Plant Physiol. 2017 Nov;175(3):1269-1282. doi: 10.1104/pp.17.01187. Epub 2017 Sep 20

TeamUp: l’agenda di dipartimento.

Gli studenti del dottorato sono invitati a consultare TeamUp, la nostra agenda di dipartimento.
TeamUp è un’agenda virtuale nella quale saranno mostrati tutti gli eventi e le attività che ospitiamo (Seminari, Congressi, Lezioni di dottorato, etc). Essa rappresenta pertanto uno strumento utile alla didattica dei dottorandi, ma anche una finestra sulle attività seminariali del Dipartimento e della Scuola Politecnica e delle Scienze di Base.
Visualizza agenda

Lezioni del dottorato

Corsi Obbligatori della Scuola Politecnica e delle Scienze di Base